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Search Results for " gne 987 "

4

Compounds

Cat No. Product Name Synonyms Targets
T11441 GNE-987 Epigenetic Reader Domain
GNE-987 is a highly active chimeric BET degrader. GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low nanomolar affinities (IC50: 4.7 and 4.4 nM, respectively). GNE-987 exhibits picomolar cell BRD...
T12798 (S)-GNE-987 Epigenetic Reader Domain
(S)-GNE-987 binds to the BRD4 BD1(IC50=4 nM) and BD2 (3.9 nM) bromodomains and can be used to design PROTAC-Antibody Conjugate (PAC).
T12551 PROTAC BRD4 ligand-1 Epigenetic Reader Domain , Ligands for Target Protein for PROTAC
PROTAC BRD4 ligand-1 is a ligand for BRD4 for Protac GNE-987 and an inhibitor of BET.
T18603 PROTAC BRD4 degrader for PAC-1 Others
PROTAC BRD4 degrader for PAC-1 (compound 5) is a chimeric BET degrader GNE-987 conjugated with a disulfide-containing linker[1]. This PROTAC-linker conjugate specifically targets and degrades BRD4, enabling selective pro...
TargetMol